Study to investigate CA7S metabolite’s role as a novel T2DM therapy

Researchers at Brigham and Women’s Hospital have been awarded a US$3.3M National Institutes of Health Grant to evaluate the CA7S metabolite as a novel therapy for type 2 diabetes; uncover how CA7S production is regulated by the gut microbiome; and determine the contribution of CA7S to type 2 diabetes remission, following bariatric surgery.

Prior bariatric surgery lowers mortality and hospital admission rates for COVID patients

The outcomes from the first meta-analysis reporting the possible protective effects of bariatric surgery in patients with COVID-19 infection indicates that prior bariatric surgery is associated with a lower rate of mortality and hospital admission in patients with obesity who become infected with SARS-CoV-2, according to researchers from the Cleveland Clinic, OH.

Device provides the feeling of fullness by stimulating the endings of the vagus nerve with light

Researchers at Texas A&M have designed a device that stimulates the endings of the vagus nerve, which is responsible for the regulation of food intake and might help with weight loss via a simple operative procedure for implantation. Researchers said their centimeter-sized device provides the feeling of fullness by stimulating the endings of the vagus nerve with light. Unlike other devices that require a power cord, their device is wireless and can be controlled externally from a remote radio frequency source.

Women with obesity have increased risks for postpartum haemorrhage complications

Researchers at the University of South Florida Health (USF Health) and Tampa General Hospital (TGH), examining how obesity affected the management and outcomes of postpartum haemorrhage have reported that high-risk obstetric patients, such as women with obesity, may need some additional support or a different treatment protocol for postpartum haemorrhage. The findings, ‘The Impact of Obesity on the Management and Outcomes of Postpartum Hemorrhage’, were published in the American Journal of Perinatology.

Brown fat may protect against numerous chronic diseases

A new study including over 52,000 participants has reported that those who had detectable brown fat were less likely than their peers to suffer cardiac and metabolic conditions ranging from type 2 diabetes to coronary artery disease.

The study, ‘Brown adipose tissue is associated with cardiometabolic health', published in Nature Medicine, by far the largest of its kind in humans, confirms and expands the health benefits of brown fat suggested by previous studies.