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AI analysis finds huge public interest in GLP-1 drugs for weight loss and mental health benefits

Using a large language models (LLMs) to analyse over 391,000 unique discussions related to glucagon-like peptide-1 (GLP-1) receptor...

SH2B1 gene mutation play an important role in regulating food intake

Researchers from the University of Michigan have identified where a gene called SH2B1 is acting inside the paraventricular hypothalamus...

Harnessing network of CNS proteins could increase effectiveness of GLP-1s

A network of proteins found in the central nervous system could be harnessed to increase the effectiveness and reduce the side effects of...

First patient enrolled in a Phase 2 Study in T2DM patients with Olatec's NLRP3 inhibitor dapansutrile

The first patient with T2DM and diabetes-related complications has been enrolled in the clinical trial, DAPAN-DIA, in Basel, Switzerland,...

EMA issues recommendations for GLP-1ra to minimise risk of aspiration and pneumonia aspiration during general anaesthesia or deep sedation

European Medicines Agency’s (EMA) Pharmacovigilance Risk Assessment Committee (PRAC) has recommended new measures to minimise the risk of...

Amylyx acquires avexitide GLP-1ra post-bariatric hypoglycaemia from Eiger BioPharmaceuticals

Amylyx Pharmaceuticals has acquired avexitide from Eiger BioPharmaceuticals, an investigational, first-in-class glucagon-like peptide-1...

Biophytis obtains IND approval to start its phase 2 OBA study in obesity

Biophytis has received Investigational New Drug (IND) approval from the FDA for its phase 2 OBA clinical study in obesity with BIO101...

Researchers discover neurons in the brain that controls food intake without causing nausea in an animal model

By teasing apart the therapeutic benefits from the adverse effects of glucagon-like peptide-1 receptor (GLP1R) agonists, researchers from...

Journal Watch 10/7/2024

Welcome to our weekly round-up of the latest bariatric and obesity-related papers published in the medical literature. As ever, we have...

Patients receiving tirzepatide were significantly more likely to achieve clinically meaningful weight loss compared with those treated receiving semaglutide

Individuals with overweight or obesity treated with tirzepatide were significantly more likely to achieve clinically meaningful weight...

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Racial and ethnic groups face barriers to obtaining OMMs

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Survey finds 50% of post-bariatric surgery patients feel less stress during the holidays

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Journal Watch 18/12/2024

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