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Journal Watch 22/1/2025
Welcome to our weekly round-up of the latest bariatric and obesity-related papers published in the medical literature. As ever, we have...

Stent-Over-Sponge as a rescue technique for leak post-bariatric surgery
The Stent-Over-Sponge (SOS) technique is safe and efficacious in dealing with post-operative leaks in patients having undergone bariatric...


STEP UP: Semaglutide 7.2mg achieves 20.7% weight loss and 18.7% regardless of treatment adherence
Novo Nordisk has announced headline results from the STEP UP study, a phase 3b trial in the global STEP programme, which revealed the...


GLP-1ra linked to cognitive benefits but could increase risk of pancreatitis and kidney conditions
Scientists at Washington University School of Medicine (WashU Medicine) in St Louis and the Veterans Affairs (VA) St Louis Health Care...


Positive results for Ascletis’ oral GLP-1ra ASC30
Ascletis Pharma has announced positive topline results from its US single ascending dose (SAD) study of ASC30 oral tablet in patients...

Jiangsu and Kailera report positive topline data for 8mg HRS9531 GLP-1/GIP
Jiangsu Hengrui Pharmaceuticals and Kailera Therapeutics have announced positive topline data from the 8mg dose of Hengrui Pharma’s Phase...


Fatty muscles increase the risk of CVD regardless of BMI
People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalised from a heart attack or heart...


Neurons that control the amount of MC4R affect how much the protein guards against obesity
Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study...


Global Commission proposes major overhaul of obesity diagnosis, going beyond BMI to define when obesity is a disease
The Lancet Commission on Clinical Obesity recommends a new, nuanced approach where measures of body fat - for example, waist...


Multi-layered omics analysis offers insight into biology and risk factors of childhood obesity
A cutting-edge molecular approach provides a detailed picture of the biological pathways associated with childhood obesity and metabolic...
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