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Significantly fewer heart attacks and strokes for bariatric patients

Bariatric surgery resulted in 60% fewer fatal and non-fatal heart attacks and strokes among 3,701 men and women who had surgery, compared to the same number of patients who did not, during an average of 11 years following the surgery. In addition, patients who had bariatric surgery lost significantly more weight (an average of over 10 kg more) and type 2 diabetes was more likely to improve to the point where the patients no longer required medication to maintain normal blood sugar levels.

Bariatric surgery reduces CRC risk in patients with obesity

Bariatric surgery significantly reduces colorectal cancer (CRC) risk in patients with obesity to the extent that they share the same risk of colorectal cancer as the general population, according to researchers from Université Côte d’Azur, Nice, France. However, for patients with obesity who do not undergo bariatric surgery, the risk is 34% above that of the general population.

Why losing weight is a battle with biology and your environment

Weight loss should not be the primary motivation behind healthy lifestyle changes, according to researchers from the University of Alberta, Canada, who claim that there is a growing body of research showing that upwards of 95 percent of those who achieve any sort of meaningful weight loss will pack it back on, and then some, within a couple of years.

How obesity causes hypertension and potential treatments

Researchers at the University of Virginia School of Medicine have discovered why obesity causes high blood pressure and identified potential ways of treating that form of high blood pressure. Small arteries in our body control blood pressure. Scientists have suspected that hypertension in obesity is related to problems in endothelial cells that line these small arteries. The reasons for this, however, have been unclear, until now. The researchers have already confirmed their discovery in human tissue samples and used it to reverse high blood pressure in lab mice.

Obesity affects the ability to work especially in women over 50

Older workers with obesity are at a higher risk of prolonged sickness absence or losing their jobs for health reasons than those of normal weight, with women affected significantly more than men, according to researchers from the University of Southampton. The study studied investigated the association between BMI and prolonged sickness absence, cutting down at work and health-related job loss among 2,299 men and 2,425 women aged between 50 and 64 years.

Brain response to liraglutide may inform future treatments

A preclinical study from the Perelman School of Medicine at the University of Pennsylvania, has shown how the weight loss drug, liraglutide, crosses the brain's blood barrier to engage with a region of the brainstem known as the nucleus tractus solitarius (NTS), which is responsible for balancing food intake and energy expenditure. Filling this gap meets a need that has become a priority for researchers looking for new treatments to help fight the increasing rates of obesity.

Negative attitudes around weight gain are pervasive in the NHS

The UK's National Health Service (NHS) needs to do more to address the ingrained stigma and discrimination faced by people with obesity, according to Dr Stuart Flint, Associate Professor in the Psychology of Obesity at the University of Leeds, who believes that negative attitudes around weight gain are pervasive in the NHS and they can affect the way patients are treated.

Mice brain cells change shape after a meal impacting satiety

Researchers from the CNRS, Inrae, University of Burgundy, Université de Paris, Inserm and University of Luxembourg have just revealed the mechanisms in the brain that lead to feelings of satiety after eating – and involve a series of reactions triggered by a rise in blood glucose levels.

Obesity should be considered sign of premature aging

Obesity should be considered a sign of premature aging, according to researchers from Concordia University, who argue that obesity predisposes people to acquiring the kinds of potentially life-altering or life-threatening diseases normally seen in older individuals: compromised genomes, weakened immune systems, decreased cognition, increased chances of developing type 2 diabetes, Alzheimer's disease, cardiovascular disease, cancer and other illnesses.

New disease classification system for obesity proposed

Researchers are proposing a new scientifically correct and medically actionable disease classification system for obesity, according to a paper published online in Obesity, the journal of The Obesity Society. The proposed disease classification system is based on the concept Adiposity-Based Chronic Disease (ABCD), a diagnostic term reflecting the pathophysiology and clinical impact of obesity as a chronic disease.

The proposed new coding system has four domains:

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