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metabolic syndrome

Computational tool predicts progression of MetS in mice

Scientists have developed a computational model that accurately predicts the gradual, long-term progression of metabolic syndrome in mice. The model, created by Dr Yvonne Rozendaal of Eindhoven University of Technology in the Netherlands and colleagues, describes glucose, lipid, and cholesterol metabolism—central factors in metabolic syndrome.

Uric acid and metabolic syndrome highlight need for screening

Twenty percent of the population have elevated levels of uric acid, increasing their risk for gout, kidney stones, metabolic syndrome, obesity, diabetes and early death, according to investigators at the Buck Institute for Research on Aging.

Lack of vitamin D in post-menopausal women linked to MetS

There is a strong association between vitamin D deficiency and metabolic syndrome (MetS) in postmenopausal women, according to the results of a study by researchers from Brazil. Investigators at São Paulo State University's Botucatu Medical School (FMB-UNESP) detected MetS in 57.8 percent of the women analysed with vitamin D insufficiency (20-29 nanograms per milliliter of blood) or deficiency (less than 20ng/ml) and in only 39.8 percent of participants with sufficient vitamin D (30ng/ml or more).

Gut microbiota - therapeutic target for metabolic syndrome

Manipulating gut microbiota through the administration of prebiotics or probiotics may assist in weight loss and reduce plasma glucose and serum lipid levels, decreasing the incidence of cardiovascular diseases and type 2 diabetes mellitus, according to a paper, ‘Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics’, published in Cell and Bioscience by researchers from The First Affiliated Hosp

Bacterial and mammalian genes and metabolic disease

Experiments in mice by researchers at Joslin Diabetes Center have highlighted the ways in which the host's genes interact with the microbial genes to increase a person’s risk of developing type 2 diabetes, obesity and the related conditions that make up metabolic syndrome.  which has become a global health epidemic. Humans and animal models with diabetes and obesity have different gut bacteria than those who don't, and when scientists transfer microbiota from obese humans or animals to germ-free animals, the recipients are more likely to become obese or diabetic.

More than a third of Americans have metabolic syndrome

Nearly 35 percent of all US adults and 50 percent of those 60 years of age or older were estimated to have the metabolic syndrome in 2011-2012, according to a study ‘Prevalence of the Metabolic Syndrome in the United States, 2003-2012.’, published in JAMA.

Bypass predicts remission from metabolic syndrome

Long limb laparoscopic Roux-en-Y gastric bypass in obese patients is a safe procedure that results in significant and sustained percentage of excess BMI lost (%EBMIL), which predicts a high remission rate of metabolic syndrome and allows discontinuation of drug therapy for associated metabolic disturbances, according to a paper published in the journal Diabetology & Metabolic Syndrome.

Obesity is a risk factor of heart disease regardless of MetS

Being overweight or obese are risk factors for myocardial infarction and ischemic heart disease, regardless of whether individuals also metabolic syndrome, according to a study published by JAMA Internal Medicine.

Variety of factors impact on effectiveness of surgery

The impact of bariatric surgery on risk factors for cardiovascular disease depends on a variety of factors, including the type of surgery, sex of the patient, ethnic background, and pre-surgery body mass index, according to a Kaiser Permanente study published in Annals of Surgery.

Hypovitaminosis D is associated with MS in the obese

A powerful association exists between hypovitaminosis D and metabolic syndrome in obese patients that is independent from body fat mass and its clinical correlates, according to a study titled 'Hypovitaminosis D is Independently Associated with Metabolic Syndrome in Obese Patients', published in Plos One.

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