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Cleveland Clinic calculator estimates ten-year risk of T2DM complications

A new risk calculator developed by Cleveland Clinic researchers can show patients who are struggling with type 2 diabetes and obesity their risks of developing major health complications over the next ten years depending on which course of treatment they choose. The research was presented as one of the Top 10 studies at the ObesityWeek 2019 international conference in Las Vegas.

Patients with obesity have better outcomes than severe patients

A study has found that bariatric surgery improves or resolves diabetes, reduces heart attacks and strokes and produces significant weight loss in patients who are 50 to 70lbs overweight (BMI<35) and that these patients are even more likely to reach a healthy weight, have a higher quality of life and improve or resolve their type 2 diabetes. The findings were presented today by researchers from the University of Michigan (U-M) at the 36th American Society for Metabolic and Bariatric Surgery (ASMBS) Annual Meeting at ObesityWeek 2019.

Diabetes rates nearly double for Japanese-Americans

Japanese-American adults who are not obese have a much higher prevalence of diabetes than non-obese non-Hispanic white Americans (8.0% vs. 4.5%), according to researchers at the University of Victoria, University of Toronto, and University at Albany, SUNY.

Gene therapy reduced obesity and reversed type 2 diabetes in mice

Researchers from Hanyang University, Seoul, in South Korea, have successfully developed a gene therapy that specifically reduced fat tissue and reversed obesity-related metabolic disease in obese mice. To overcome the side effects of current anti-obesity drugs, researcher Dr Jee Young Chung and colleagues developed a specific gene silencing therapy against a fatty acid metabolism gene, Fabp4.

Whole body vibration can reduce inflammation in diabetes

Whole body vibration appears to improve how well our body uses glucose as an energy source and adjust our microbiome and immune cells to deter inflammation, according to researchers from Medical College of Georgia and Dental College of Georgia at Augusta University. For the first time, they have described how regular use of whole body vibration can create this healthier mix by yielding a greater percentage of macrophages - cells that can both promote or prevent inflammation - that suppress rather than promote.

New US diabetes cases fall as obesity rises

The number of new diabetes cases among US adults keeps falling, even as obesity rates climb, according to research led by Dr Stephen Benoit of the Centers for Disease Control and Prevention. The new federal data revealed the number of new diabetes diagnoses fell to about 1.3 million in 2017, down from 1.7 million in 2009, a decline that has been going on for close to a decade. However, health officials are not celebrating.

ZGN-1061 trial shows clinically significant 1.1% reduction of A1C

Zafgen has announced positive data for the second cohort of its Phase 2 clinical trial of ZGN-1061, designed to evaluate efficacy and safety in patients with type 2 diabetes and the likely therapeutic dose range of ZGN-1061 up to 1.8mg. The clinical trial met all of its primary objectives at the 1.8mg dose, which included glycaemic control or change in A1C, and safety and tolerability.

Very low-calorie diets trialled by NHS to tackle diabetes

Hundreds of thousands of people in the England will receive NHS help to battle obesity and type 2 diabetes in a programme that will not only improve the health of patients but also save the NHS money that can be reinvested in frontline care. Currently, the health service in England spends around 10 percent of its budget on treating diabetes.

Alcohol intake and long-term weight loss for diabetics

A study from the University of Pennsylvania School of Nursing (Penn Nursing) suggests that alcohol consumption may attenuate long-term weight loss in adults with Type 2 diabetes. Although research shows that losing weight can help prevent or delay the onset of diabetes and achieving this often includes decreasing or eliminating calories from alcohol, few studies examine whether people who undergo weight loss treatment report changes in alcohol intake and whether alcohol influences their weight loss.

Bariatric surgery reduces coronary heart disease risk by 40 percent

Patients with severe obesity who get weight-loss surgery cut their risk of developing coronary heart disease by about 40 percent, according to a new study from Cleveland Clinic Florida researchers who presented their findings at ObesityWeek 2018, hosted by the American Society for Metabolic and Bariatric Surgery (ASMBS) and The Obesity Society (TOS).

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