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weight gain

Studies demonstrate the effectiveness of post-op liraglutide

Liraglutide can be considered as a safe and effective adjunctive treatment to prevent weight regain after bariatric surgery, according to two studies presented at the UK’s Society for Endocrinology annual conference.

In the first study, ‘Efficacy of liraglutide in weight management post bariatric surgery patients: data from an Emirati cohort’, researchers from Imperial College London Diabetes Centre, Abu Dhabi, UAE, assessed the use of Liraglutide for relapse after bariatric surgery in an Emirati population.

Weight gain in early adult life associated with risk of premature death

Gaining weight from your mid-20s into middle age is associated with an increased risk of premature death, according to a study of US adults by researchers from Huazhong University of Science and Technology, Wuhan, China. Weight loss at older ages (from middle to late adulthood) was also linked to higher risk and the findings highlight the importance of maintaining normal weight throughout adult life to reduce the risk of premature death, the researchers explained.

People with obesity have more satisfaction from food

The propensity to overeat may, in part, be a function of the satisfaction derived from eating, according to a study by researchers from the University of Iowa, Iowa City, IA. The study found no significant difference in taste perceptions between participants of normal weight and those who were overweight.

FTO gene variation linked to weight gain and obesity in children

Researchers from Columbia University Irving Medical Center have discovered that children who do not have obesity, but who are at risk for the chronic disease due to a common genetic variant eat more. Led by Dr Michael Rosenbaum,of Columbia University Irving Medical Center's Department of Pediatrics Division of Molecular Genetics, he and colleagues explained that many existing studies of children at risk for increased adiposity include those who already have obesity.

How the brain influences our eating habits and weight gain

Two separate teams of researchers have identified how genes involved in neural development can affect body weight and how brain cells involved in memory play an important role after a meal in reducing future eating behaviour. The first team – led by investigators at the University of Cambridge and Children's Hospital Los Angeles (CHLA) have pinpointed a set of molecules that wire the body weight centre of the brain.

Neuroinflammation protects women from weight gain

A research team at the University of California, Riverside, has found that only male mice experienced neuroinflammation or activation of the immune system's response in the brain, after being fed a high-fat diet. While females were unaffected, males showed low testosterone and reduced sperm count, in addition to neuroinflammation. The study results, 'Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice,' were published in Frontiers in Immunology

People with severe obesity have lonely and prolonged struggle

The majority of people with severe obesity have a lonely and prolonged struggle with their weight, according to the latest paper form the Swedish Obese Subjects (SOS) study, which focused on the control group (non-surgical) included in the study. The study analysed self‐reported weight‐loss methods and weight changes over ten years and found that 83 percent were constantly striving to lose weight or prevent weight gain.

Abnormal lipid metabolism predicts weight gain and T2DM in women

The inefficient breakdown of fats predicts later weight gain and metabolic complications such as type 2 diabetes in women, according to researchers from the Karolinska Institutet. Low levels of hormone-stimulated lipolysis - a biochemical process by which triglycerides are broken down into energy-rich fatty acids - were associated with weight gain and metabolic problems 13 years later. Based on the findings, the researchers developed an algorithm to detect impairments in hormone-stimulated lipolysis using clinical and blood measures.

Chronic stress-hormone pulses controls weight gain

A study by Stanford University School of Medicine researchers has provided the first molecular understanding of why people gain weight due to chronic stress, disrupted circadian rhythms and treatment with glucocorticoid drugs. According to the researchers, it is related to the timing of the dips and rises of a class of hormones called glucocorticoids - predominantly the stress hormone cortisol - according to a new study by Stanford University School of Medicine researchers.

Serotonin associated with weight gain and calorie control

Serotonin play a significant role in the body's weight gain and calorie control, according to researchers from Flinders University, SAHMRI and the University of Adelaide. It has been known for years that serotonin is a contributor to feelings of happiness and sadness however, this latest study has reported that elevated concentrations of serotonin, the crucial neurotransmitter that chemically transmits messages to nerve cells in the body, is also linked to obesity, and the researcher stated that more research into serotonin could reduce obesity rates.

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