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News about clinical research: trials, studies, case reports, etc.

EarlyBird results shows why children are at risk of future T2DM

Researchers at the University of Plymouth and Nestlé have revealed new insights into the factors that predispose children to developing type 2 diabetes in adult life. The EarlyBird study followed 300 healthy children in Plymouth, UK, from five years of age to early adulthood to explore how the metabolism changes during growth for 15 years and determine who would become at risk of developing type 2 diabetes, and why.

Key strategies to maintaining sustained weight loss

A study by researchers from California Polytechnic State University, San Luis Obispo, California, US, has reported that that if you want to lose weight and keep it off, building healthy dietary, self-monitoring and psychological coping strategies may be the keys to success.

Adolescents with obesity and PCOS have more 'unhealthy' bacteria

Teens with obesity and polycystic ovary syndrome (PCOS) have more ‘unhealthy’ gut bacteria suggesting the microbiome may play a role in the disorder, according to researchers from Children's Hospital Colorado in Aurora, CO.

Case study: Oesophageal perforation following LSG

The risks related to the use of bougie during bariatric surgery should not be underestimated and inserted with extreme caution in order to prevent oesophageal perforations, according to researchers from Karolinska University Hospital, Stockholm, Sweden, who noted that oesophageal perforations are a challenging, life threatening complication where prompt diagnosis and adequate treatment are essential.

Artec EVA 3D scanner can detect post-op body shape changes

Utilising the Artec EVA three-dimensional (3D) mobile imaging scanner can provide an objective and reproducible source for the detection of body shape changes after bariatric surgery, according to researchers from RWTH Aachen University Hospital, Aachen, Germany, who recommended its use when evaluating central obesity, especially for research issues and body imaging before and after bariatric surgery.

Lack of exposure to sunlight linked with metabolic health decline

Exposure to light regulates how two kinds of fat cells work together to produce the raw materials that all other cells use for energy and disruptions to this fundamental process appear to have a negative effect on our metabolic health, according to investigators from Cincinnati Children's who were studying how mice control their body temperature.

Abdominal obesity increases risk of recurrent myocardial infarction

Patients who have suffered a myocardial infarction and who carry excess abdominal fat are at increased risk of another heart attack, according to a study led by researchers from the Karolinska Institute, Sweden. Prior studies have shown that abdominal obesity is an important risk factor for having a first heart attack. But until now, the association between abdominal obesity and the risk of a subsequent heart attack or stroke was unknown.

FINDRISC prediction tool overestimates T2DM risk

The Finnish Diabetes Risk Score (FINDRISC) questionnaire, used extensively to predict a person's degree of risk for getting type 2 diabetes, does not adequately identify the most vulnerable individuals, according to researchers from Norway.

Removing gastric balloons without using endoscopy

Researchers at Massachusetts Institute of Technology (MIT) have potentially found a way to eliminate some of the endoscopic surgeries needed to remove gastrointestinal (GI) medical devices, such as gastric balloons and oesophageal stents. Clinicians use these devices to diagnose, treat and monitor GI disorders, many of which require endoscopic procedures to remove them once they are no longer needed.

The first and only procedureless intragastric balloon for safe and rapid weight-loss

First launched in 2015, over 20,000 Elipse Balloon has now been distributed in +30 countries. The Elipse Balloon, a new category weight loss product, is proven to be an effective, non-surgical weight-loss treatment. Clinical trials have shown that it typically results in 10% to 15% total body weight loss, with an average loss of 10-15kg1-10.

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