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Journal Watch - 15/11/12

Influence of Additional Resection of the Gastric Fundus on Excessive Weight Loss in Laparoscopic Very Very Long Limb Roux-en-Y Gastric Bypass.

Researchers from Limmattal Hospital Zurich hypothesised that an additional resection of the gastric fundus in Roux-en-Y would remove some of the ghrelin-producing cells, leading to a more prominent excess weight loss and less pronounced satiety feelings. However, the modification didn’t significantly affect the clinical results, leading the researchers to conclude that the value of removing a part of the ghrelin-producing cells “may be overestimated”. (Full text)

Psychological characteristics and associations with weight outcomes two years after gastric bypass surgery: Postoperative eating disorder symptoms are associated with weight loss outcomes.

What are the psychological effects of Roux-en-Y gastric bypass surgery? According to this paper, patient questionnaire scores were significantly higher on impulse regulation, interoceptive awareness, ineffectiveness, maturity fears and interpersonal distrust, in comparison with a control group. (Full text)

Remission of diabetes in patients with longstanding type 2 diabetes following placement of adjustable gastric band: A retrospective case control study.

How successful gastric band is in causing remission of long-term type 2 diabetes is currently unclear, but in this study, only 16% of patients were in remission at 2 years. The authors conclude that there is a “clear need” for randomised studies of the effects of gastric banding in patients with long-term type 2 diabetes. (Full text)

Improved blood pressure, nitric oxide and asymmetric dimethylarginine are independent after bariatric surgery.
Do a drop in nitric oxide and a rise in asymmetric dimethylarginine cause the improved blood pressure after bariatric surgery? This study found that while plasma concentrations of these chemicals did act as expected, it was not correlated to arterial pressure, leading the researchers to conclude that other causes for the beneficial changes in blood pressure post-surgery should be considered. (Full text)

The food craving questionnaire-trait in a bariatric surgery seeking population and ability to predict post-surgery weight loss at six months.
The Food Craving Questionnaire-Trait is found to have “excellent” internal consistency in bariatric surgery-seeking patients in this study. Higher scores on a subscale measuring 'cues that may trigger food cravings were associated with greater weight loss at 6months post-surgery; higher scores on a subscale measuring guilt from cravings and/or giving into them was associated with less weight loss. (Full text)