Brown fat may protect against numerous chronic diseases

A new study including over 52,000 participants has reported that those who had detectable brown fat were less likely than their peers to suffer cardiac and metabolic conditions ranging from type 2 diabetes to coronary artery disease.

The study, ‘Brown adipose tissue is associated with cardiometabolic health', published in Nature Medicine, by far the largest of its kind in humans, confirms and expands the health benefits of brown fat suggested by previous studies.

Drug combination could improve glucose and weight control in diabetics

Scientists from Hyderabad, India, have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published in eLife. The results pave the way for clinical studies of the new drug combination as a more effective long-term treatment for millions of people with diabetes and obesity.

Unhealthy alcohol use increases after bariatric surgery

Researchers looking at the changes over time in alcohol use and unhealthy alcohol use two years after bariatric surgery have reported that for every 21 patients who undergo Roux-en-Y gastric bypass (RYGB) and every 29 patients who undergo laparoscopic sleeve gastrectomy (LSG), on average, one from each group will develop unhealthy alcohol use.

Gut microbiome organisms could play key role in treating T2DM

Researchers at Oregon State University have found organisms in the gut microbiome could play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease. A key risk factor for type 2 diabetes is being overweight, often a result of a western diet in combination with low physical activity. The paper, ‘Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes’, was published in Nature Communications.