Bariatric surgery significantly cuts the risk of developing pancreatic cancer in people with obesity and diabetes, a new 20-year analysis has found. The study, presented at UEG Week 2020 Virtual, analysed 1,435,350 patients with concurrent diabetes and obesity over a 20-year period.
Parathyroid axis monitoring could benefit patients who at high-risk of hyperparathyroidism after bariatric surgery, according to researcher from the US, who noted that patients with renal failure, hypertension and anaemia would likely benefit from earlier follow-up with parathyroid axis monitoring (outpatient monitoring of calcium, vitamin D and PTH levels). They also reported that monitoring is likely most beneficial for patients younger than 45 years of age.
Bariatric surgery could be effective in improving male’s sexual (erectile) function in patients with obesity, according to Chinese researchers, however, due to the limited number of studies evaluating this topic, the authors noted that additional studies are required to confirm their findings. The paper, ‘The relationships between bariatric surgery and sexual function: current evidence based medicine’, was published in BMC Urology.
The High Mobility Group Box-1 (HMGB1) molecule is higher in the blood of younger black adults than whites, females than males and increases with weight and age, researchers report in the first large, longitudinal study associating circulating HMGB1 levels with obesity, inflammation promoters and early indicators of cardiovascular risk in humans.
The British Obesity and Metabolic Surgery Society (BOMSS) and dendrite Clinical Systems have published the Third National Bariatric Surgery Registry (NBSR) Report that outlines the safety and effectiveness of bariatric and metabolic surgery. This latest report examines data from 19,104 Roux-en-Y gastric bypass (RYGB) procedures, 13,841 sleeve gastrectomy (SG), 4,499 gastric bands (GB) and 1,515 One Anastomosis Gastric Bypasses (OAGB) performed between 2013 and 2018. Mirroring global trends, SG replaced RYGB to become the commonest bariatric procedure in the UK in 2018.
An international group of global experts including anaesthetists, surgeons and other healthcare professionals have come together to publish a consensus statement on the prevention of opioid-related harm in adult surgical patients. The consensus statement, ‘An international multidisciplinary consensus statement on the prevention of opioid‐related harm in adult surgical patients’, was published in Anaesthesia (a journal of the Association of Anaesthetists).
There are similar overall early and late complication rates between primary and revisional robotically-assisted laparoscopic Roux-en-Y gastric bypass (RYGB), with higher rates of gastrojejunal strictures and readmissions for oral intolerance in the revisional group, according to a study by researchers from Texas. The results were reported in the paper, ‘Outcomes of primary versus revisional robotically assisted laparoscopic Roux-en-Y gastric bypass: a multicenter analysis of ten-year experience’, published online in Surgical Endoscopy.
A study by researchers at McGill University has identified polycystic ovary syndrome (PCOS) as an independent risk factor for gestational diabetes (GDM), gestational hypertension (GHTN) and preeclampsia (PEC) of pregnancy. After controlling for all potential confounding effects, women with PCOS were at a two-fold higher risk of developing GDM, a 50% increased risk for the development of GHTN and a 30% increased risk of developing PEC, compared to women without PCOS.
Researchers from the University of Oregon’s Prevention Science Institute have developed a complicated model to determine the roles nature and nurture play when it comes to children and their weight. Nature – genetics - plays a larger role, but nurture is also substantially responsible for whether a child has obesity.
Researchers at the University College London and University College London Hospitals NHS Foundation Trust), London, UK, have found that the vast majority of participants with new onset loss of smell were seropositive for SARS-CoV-2 antibodies, and this acute loss of sense of smell needs to be considered globally as a criterion for self-isolation, testing and contact tracing in order to contain the spread of COVID-19. Indeed, the authors noted that the loss of a sense of smell may be a more reliable indicator of Covid-19 than cough or fever.
In a survey of physicians, certified by the American Board of Obesity Medicine (ABOM), by researchers at Johns Hopkins Medicine, has found that these practitioners commonly offer key services supported by scientific research and clinical trials. This suggests that primary care clinicians can be increasingly confident that their patients will receive this ‘evidence-based care’ when referred to an obesity specialist.
The European Association for the Study of Obesity (EASO) and the European Coalition for People Living with Obesity (ECPO) are urging patients to continue their treatment for obesity and not to let it lapse because of fears about COVID-19. The organisations are very concerned that people seeking treatment for overweight and obesity have either postponed or stopped seeking medical advice because of fears they may be putting themselves at risk.
An editorial accompanying a study published in the Journal of the American College of Cardiology is bringing attention to the underappreciated and often overlooked issue of malnutrition among people with obesity. Malnutrition is defined as faulty nutrition due to inadequate or unbalanced intake of nutrients.
Some people are at higher risk of developing obesity because they possess genetic variants that affect how the brain processes sensory information and regulates feeding and behaviour, according to findings from scientists at the University of Copenhagen. The outcomes support a growing body of evidence that obesity is a disease whose roots are in the brain.
People who are severely overweight are less likely to be able to re-wire their brains and find new neural pathways, a discovery that has significant implications for people recovering from a stroke or brain injury. In the paper, ‘Obesity is Associated with Reduced Plasticity of the Human Motor Cortex’, published in Brain Sciences, researchers from UniSA and Deakin University report0 that brain plasticity is impaired in people with obesity, making it less likely that they can learn new tasks or remember things.
Excess fat stored around the abdomen (central fatness) is associated with a higher risk of early death from any cause, regardless of overall body fat, whereas larger hips and thighs are associated with a lower risk, according to researchers from Iran and Canada. The results suggest that measuring central fatness may be a more reliable indicator of risk of death from excess weight and could be used alongside body mass index to help determine the risk of premature death.
Five to 10 percent of surgically induced weight loss is associated with improved life expectancy and cardiovascular health compared with about 20 percent weight loss is necessary to observe similar benefits with a non-surgical treatment, according to researchers from Cleveland Clinic. In comparison. The findings also show that metabolic surgery may contribute health benefits that are independent of weight loss.
New data from the Centers for Disease Control and Prevention (CDC) show that adult obesity prevalence is increasing and adults with obesity are at heightened risk for severe outcomes from COVID-19. The ‘2019 Adult Obesity Prevalence Maps’ show that twelve states (Alabama, Arkansas, Indiana, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Oklahoma, South Carolina, Tennessee, and West Virginia) now have an adult obesity prevalence at or above 35%, an increase from nine states in 2018 and six states in 2017.
In the COVID-19 special session at the Annual Meeting of the European Association for the Study of Diabetes (EASD), Professor Juliana Chan, (The Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong, China) has presented a review of the evidence on the devastating impact COVID-19 is having on people with diabetes.
A study of approximately 200,000 blood samples from the UK Biobank has identified more than 2,000 undiagnosed cases of type 2 diabetes, according to a study presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD). As UK Biobank data is not reported back to participants, patients found to have undiagnosed diabetes waited on average more than two years for a clinical diagnosis and around a quarter remained undiagnosed five years later.