Does a strict diet explain the metabolic effect of gastric bypass surgery?

Researchers at the Lund University Diabetes Centre (LUDC) and the Centre for Analysis and Synthesis (CAS) have for the first time studied the effects of the strict low-calorie diet and the operation separately, and the results show that the diet alone accounted for the greatest positive effect. The findings are described in the paper, ‘Metabolic Effects of Gastric Bypass Surgery - is it all about Calories?’, published in the journal Diabetes

Obalon enters consulting agreement for coverage and reimbursement of balloon system

Obalon Therapeutics has executed a consulting agreement with Blue Ox Healthcare Partners, a private equity firm focused on commercial-ready companies bringing technology enabled innovation to healthcare, especially those involved in precision health, healthcare delivery and affordability.

Echelon Stapling System associated with lower rates of bleeding-related complications vs. Signia Stapling System

The Echelon Powered Stapler with Gripping Surface Technology (GST) reloads (Ethicon) was associated with a lower rate of bleeding-related complications compared to the Signia Stapling System with Tri-Staple (Medtronic) among patients undergoing laparoscopic sleeve gastrectomy, according to the first real-world evidence study comparing these two powered surgical stapling systems.

Researchers provide new insight into hyperglycaemia in COVID-19 severity

Researchers from Michigan Medicine team has providing new insights into why patients with severe hyperglycaemia may trigger worse outcomes in people infected with COVID-19. The researchers have developed a blood sugar management tool that may potentially reduce risk of secondary infections, kidney issues and intensive care stays in people with diabetes, prediabetes or obesity who get COVID-19. The reported their findings in the paper, ‘Managing Hyperglycemia in the COVID-19 Inflammatory Storm’, published in Diabetes.

Lipoic acid supplements aids weight loss

A compound given as a dietary supplement to overweight but otherwise healthy people in a clinical trial caused many of the patients to lose weight, according to research by Oregon State University and Oregon Health & Science University. The research, ‘A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations’, was published in The Journal of Nutrition.

Fat cell chemicals associated with increased breast cancer risk in women with obesity

Obesity increases the release of tumour-promoting molecules from fat tissue and is associated with an increased risk of breast cancer, according to a study, ‘Obese adipose tissue extracellular vesicles raise breast cancer cell malignancy’, published in Endocrine-Related Cancer.

Bile component lowers high blood sugar after bariatric surgery

A study from Harvard Medical School (UMS) and Brigham and Women's Hospital reveals the latest piece of the puzzle of how bariatric surgery can lead to healthier blood sugar levels. The paper, ‘Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects’, published in Nature Chemical Biology, reports that that a specific bile acid rises in the guts of mice and humans after bariatric surgery and sets off a chain of biochemical events that lowers high blood sugar.

Nestlé and Epitomee to develop and commercialise polymer-based ingestible weight loss product

Nestlé Health Science and Epitomee Medical have entered into a strategic partnership for the development and commercialisation of an innovative polymer-based ingestible product aimed at promoting weight loss and improving health. The strategic partnership will cover the development and the commercialisation of the product which has already demonstrated efficacy and safety in various pre-clinical and clinical studies with significant weight loss reduction and other beneficial health impacts.

40 percent mortality rate for patients denied bariatric surgery

Researchers at Beth Israel Deaconess Medical Center (BIDMC) who followed up 107 patients who were denied the procedure in 2007, have reported that most patients who were initially turned away eventually obtained bariatric surgery, experienced improved overall health and were still living at 12- year follow up. However, 40 percent of those denied surgery in 2007 who never underwent the procedure were deceased by 2019.

‘Returning to surgery’ – the views of bariatric and metabolic experts

As bariatric and metabolic surgery restarts across the world, Bariatric News spoke to Shaw Somers about how the bariatric community can safely resume surgery... 

1. Although the pandemic has sadly resulted in the loss of many people, the risk of dying from the virus is low for most people (some 80% are asymptomatic). What can be done to reassure patients thinking about bariatric surgery but who are also worried about possibly acquiring the virus in hospital or shortly after their procedure?