Enara accelerates weightloss telehealth programme to combat COVID-19

Enara Health, a developer of a technology-powered personalised weight loss programme, is expanding telehealth availability of its programme to all residents in California, Texas and Illinois. This rollout represents an earlier-than-planned first stage of a US rollout of the Enara Health platform, a clinical weight loss programme that takes a multi-faceted approach to obesity treatment.

Mice brain cells change shape after a meal impacting satiety

Researchers from the CNRS, Inrae, University of Burgundy, Université de Paris, Inserm and University of Luxembourg have just revealed the mechanisms in the brain that lead to feelings of satiety after eating – and involve a series of reactions triggered by a rise in blood glucose levels.  The study, ‘Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal’,  which was conducted on mice, was published in Cell Reports.

Clear association between COVID-19 disease severity and obesity

There is a clear relationship between obesity and the severity of COVID-19 disease, according to research presented by François Pattou, Professor of Surgery at the Faculty of Medicine of the University of Lille, and head of the Department of General and Endocrine Surgery at Lille University Hospital, France, at this year's European and International Congress on Obesity.

Novel combination therapy tethering T2DM drugs increases efficacy

Biomedical engineers at Duke University have shown that the efficacy of a two-pronged type 2 diabetes treatment increases when the drugs are linked by a heat-sensitive tether rather than simply concurrently administered. The combination molecule is formed by an elastin-like polypeptide (ELP) linker that forms a gel-like depot when injected under the skin, which slowly dissolves and releases the active drug over time.

Excess weight whilst pregnant could interfere with infant’s brain development

 

Expectant mothers with obesity may hinder the development of the babies' brains as early as the second trimester, according to a new study led by researchers at NYU Grossman School of Medicine. The study linked high body mass index (BMI) to changes in two brain areas, the prefrontal cortex and anterior insula. These regions play a key role in decision-making and behaviour, with disruptions having previously been linked to attention-deficit/hyperactivity disorder (ADHD), autism and overeating.

SOPHIA consortium: improving risk assessment of comorbidities and treatment for people with obesity

Twenty-nine leading international partners have joined forces to establish a research consortium Stratification of Obese Phenotypes to Optimize Future Obesity Therapy (SOPHIA) with the aim of improving risk assessment of comorbidities and treatment for people with obesity. Obesity complications are common, but predicting who will develop any of the 200 known complications of obesity is extremely difficult. Moreover, there are insufficient predictors for who will respond to obesity treatments.

Childhood obesity rates could increase if schools stay closed

The childhood obesity rate may increase 2.4% or 1.27 million children if school closures to prevent the spread of the coronavirus continue into December, according to the study, ‘Projecting the impact of COVID-19 pandemic on childhood obesity in the U.S.: A microsimulation model’, published in the Journal of Sport and Health Science.