Brown fat can continue to grow and divide, even after birth, according to researchers at Masonic Medical Research Institute (MMRI), the findings could have major implications for treating obesity as increasing the overall number of these cells to prevent or reduce the onset of obesity. It was previously thought that individuals were born with only a finite number of brown fat cells.
Seven-year outcomes from the SLEEVE vs byPASS (SLEEVEPASS) randomised clinical trial has reported that laparoscopic Roux-en-Y gastric bypass resulted in greater weight loss than laparoscopic sleeve gastrectomy LSG however, the difference was not clinically relevant based on the prespecified equivalence margins. Interestingly, there was no difference in long-term quality of life (QoL) between the procedures, and surgery was associated with significant long-term Disease-specific QoL (DSQoL) improvement, with greater weight loss was associated with better DSQoL.
Harvard Medical School (HMS) researchers have discovered that obesity allows cancer cells to outcompete tumour-killing immune cells in a battle for fuel, findings that could have significant implications for cancer immunotherapy.
An exercise intervention programme after bariatric surgery is an effective strategy to improve bone health, according to researchers from Portugal. Although weight loss surgery is a highly effective treatment for obesity, some studies have shown that it can be detrimental to bone health. The study, ‘The Effect of an Exercise Intervention Program on Bone Health After Bariatric Surgery: A Randomized Controlled Trial’, published in the Journal of Bone and Mineral Research suggests that exercise may help address this shortcoming.
A greater obesity duration is associated with worse values for all cardiometabolic disease factors, according to a study by Dr Tom Norris of Loughborough University, UK, and colleagues. The study, 'Duration of obesity exposure between ages 10 and 40 years and its relationship with cardiometabolic disease risk factors: A cohort study', was published in PLoS Medicine.