Gastric bypass surgery patients may face increased fracture risk

Patients who have bariatric surgery may face an elevated risk of bone fractures, according to a Swedish study investigating the association between different bariatric surgery procedures and fracture risk. The paper, ‘Fracture risk after three bariatric surgery procedures in Swedish obese subjects: up to 26 years follow‐up of a controlled intervention study’, published in the Journal of Internal Medicine

Obesity affects the ability to work especially in women over 50

Older workers with obesity are at a higher risk of prolonged sickness absence or losing their jobs for health reasons than those of normal weight, with women affected significantly more than men, according to researchers from the University of Southampton. The study studied investigated the association between BMI and prolonged sickness absence, cutting down at work and health-related job loss among 2,299 men and 2,425 women aged between 50 and 64 years.

Brain response to liraglutide may inform future treatments

A preclinical study from the Perelman School of Medicine at the University of Pennsylvania, has shown how the weight loss drug, liraglutide, crosses the brain's blood barrier to engage with a region of the brainstem known as the nucleus tractus solitarius (NTS), which is responsible for balancing food intake and energy expenditure. Filling this gap meets a need that has become a priority for researchers looking for new treatments to help fight the increasing rates of obesity.

Mice brain cells change shape after a meal impacting satiety

Researchers from the CNRS, Inrae, University of Burgundy, Université de Paris, Inserm and University of Luxembourg have just revealed the mechanisms in the brain that lead to feelings of satiety after eating – and involve a series of reactions triggered by a rise in blood glucose levels.  The study, ‘Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal’,  which was conducted on mice, was published in Cell Reports.