BAMBINI trial to compare bariatric surgery vs lifestyle intervention for PCOS

Researchers led by Imperial College Healthcare NHS Trust, London, UK, are looking to recruit participants to enrol in the Bariatric surgery vs. Medical care for obesity and polycystic ovarian syndrome related infertility (BAMBINI) randomised clinical trial. The study will examine the effects of bariatric surgery vs. lifestyle intervention in premenopausal women over the age of 18 with a diagnosis of polycystic ovarian syndrome (POCS) with a body mass index ≥35kg/m2 and less than eight menstrual periods a year.

Losing 13% of body weight demonstrates benefits for metabolic conditions

People with obesity who intentionally (not because of illness) lost an average (median) 13% of their initial body weight reduced their relative risk of developing type 2 diabetes by 42%-44%, sleep apnoea by 22%-27%, high blood pressure by 18%-25%, and dyslipidaemia by 20-22%, according to a study of over 550,000 adults in primary care in the UK. The study authors believe it is the first of its kind to quantify the benefits of intentional weight loss on the risk of obesity-related conditions in real-world clinical practice.

UK: People with obesity wait longer for obesity consultation

A detailed analysis of UK data from a global obesity study (the ACTION-IO study) has shown that, on average, people with obesity (PwO) in the UK were struggling with their weight for nine years before they sought help from a healthcare professional/HCP, much longer than the global average of six years. This delay puts PwO at additional risk of developing obesity-related conditions such as type 2 diabetes (T2D), obstructive sleep apnoea (OSA) and cancer. Additionally, more than half of the PwO had never discussed their weight with an HCP.

SOReg: T2DM patients should have bariatric surgery earlier

The latest findings from the annual Scandinavian Obesity Surgery Registry (SOReg) report could challenge existing recommendations and clinical practice for bariatric surgery and type 2 diabetes (T2DM) patients, according to the authors of a summary paper of the report, ‘Bariatric Surgery: There Is a Room for Improvement to Reduce Mortality in Patients with Type 2 Diabetes’, published in Obesity Surgery.