Older workers with obesity are at a higher risk of prolonged sickness absence or losing their jobs for health reasons than those of normal weight, with women affected significantly more than men, according to researchers from the University of Southampton. The study studied investigated the association between BMI and prolonged sickness absence, cutting down at work and health-related job loss among 2,299 men and 2,425 women aged between 50 and 64 years.
A preclinical study from the Perelman School of Medicine at the University of Pennsylvania, has shown how the weight loss drug, liraglutide, crosses the brain's blood barrier to engage with a region of the brainstem known as the nucleus tractus solitarius (NTS), which is responsible for balancing food intake and energy expenditure. Filling this gap meets a need that has become a priority for researchers looking for new treatments to help fight the increasing rates of obesity.
Researchers from the CNRS, Inrae, University of Burgundy, Université de Paris, Inserm and University of Luxembourg have just revealed the mechanisms in the brain that lead to feelings of satiety after eating – and involve a series of reactions triggered by a rise in blood glucose levels. The study, ‘Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal’, which was conducted on mice, was published in Cell Reports.
Coinciding with World Obesity Day, over 100 medical and scientific organisations have pledged their support for a consensus statement that recognises unscientific public narratives of obesity as a major cause of weight stigma and calls for strong policies and legislation to prevent weight-based discrimination.