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Probiotic supplements could enhance weight loss in children

Probiotic supplements may enhance weight loss and improve the metabolic health of children with obesity following a diet and exercise plan, according to research presented at the 58th Annual European Society for Paediatric Endocrinology Meeting, in Vienna, Austria. The findings of this small trial suggest that probiotic supplements may help obese children lose body weight and also reduce their risk of future metabolic conditions, including type 2 diabetes and heart disease.

Dysfunctional eating patterns can be triggered by early life experiences

Dysfunctional eating patterns and habits in overweight and obese adults can be triggered by early life experiences that are deeply rooted within patients' personality features, meaning weight loss interventions such as bariatric surgery and cognitive-behaviour therapy might not be sufficient to guarantee long-term success.

Obesity linked to a six-fold increased risk of T2DM

Obesity is linked to a nearly 6-fold increased risk of developing type 2 diabetes mellitus (T2DM), with high genetic risk and unfavourable lifestyle also increasing risk but to a much lesser extent, according to research presented at the Annual Meeting of the European Association for the Study of Diabetes in Barcelona, Spain by Hermina Jakupovic, University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research, Copenhagen, Denmark, and colleagues.

Young females with obesity are at early risk for cardiovascular disease

Progesterone could put females at an increased, early risk for cardiovascular disease, according to investigators at the Medical College of Georgia at Augusta University. Premenopausal women are considered protected from cardiovascular disease, but evidence indicates obesity can negate those benefits, and in fact put them at even higher risk than men, but just how remains an unfolding mystery.

Study shows why people gain weight as they get older

Researchers at Karolinska Institutet, in Sweden, have uncovered why many people struggle to keep their weight in check as they get older. According to the study, the lipid turnover in fat tissue decreases during ageing and makes it easier to gain weight, even if one does not eat more or exercises less than before.

LSG improves symptoms in patients with depression

Laparoscopic sleeve gastrectomy (LSG) is an effective surgery for weight loss as the main goal even among patients who suffers from depression, according the researchers from Assuta Medical Center, Tel-Aviv, in Israel. They reported that LSG was associated with improvements in family relationships, self-esteem and produces a high index of satisfaction, mainly due to weight loss.

Gene therapy reduced obesity and reversed type 2 diabetes in mice

Researchers from Hanyang University, Seoul, in South Korea, have successfully developed a gene therapy that specifically reduced fat tissue and reversed obesity-related metabolic disease in obese mice. To overcome the side effects of current anti-obesity drugs, researcher Dr Jee Young Chung and colleagues developed a specific gene silencing therapy against a fatty acid metabolism gene, Fabp4.

Role of 27-hydroxycholesterol molecule in obesity

A single cholesterol-derived molecule, called 27-hydroxycholesterol (27HC) will increase body fat, even if you do not eat a diet filled with red meat and fried food. That kind of diet, however, will increase the levels of 27HC and body weight.

Obesity is associated with reduced taste responses and perception

An animal study by researchers at the Binghamton University, State of University of New York, has shown that obesity is associated with reduced taste responses and perception. The researchers explained that there have been anecdotal evidence showing that obesity reduces taste perception and that obese people tend to enjoy and savour their food less. However, this has never been proven.

Weight loss is achievable regardless of psychiatric medication use

Individuals who take anti-depressants and/or anti-psychotics and participate in a weight management programme can lose weight whether or not they take psychiatric medications, according to a study by Canadian researchers. The investigation is the first to examine weight loss outcomes in individuals taking anti-depressants or anti-psychotics alone, in combination or not at all.

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