Gastric bypass improves muscle strength and physical performance

Roux-en-Y gastric bypass (RYGB) improves relative muscle strength and physical performance in people with obesity, according to a study led by researchers from the University of California, San Francisco, San Francisco, CA. However, as well as... (more)

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21/01/19 - News

Owen Haskins

ZGN-1061 trial

ZGN-1061 trial shows clinically significant 1.1% reduction of A1C

Zafgen has announced positive data for the second cohort of its Phase 2 clinical trial of ZGN-1061, designed to evaluate efficacy and safety in patients with type 2 diabetes and the likely therapeutic dose range of ZGN-1061 up to 1.8mg. The clinical trial met all of its primary... (more)

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21/01/19 - News

Owen Haskins

The brain and hunger

How the brain influences our eating habits and weight gain

Two separate teams of researchers have identified how genes involved in neural development can affect body weight and how brain cells involved in memory play an important role after a meal in reducing future eating behaviour. The first team – led by investigators at the... (more)

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18/01/19 - News

Owen Haskins

Revita System US study

Type 2 diabetes Revita System study launches in US

A same-day procedural therapy to improve glucose control for Type 2 diabetes patients will be investigated in a pilot study at The University of Texas Health Science Center at Houston (UTHealth). Drs Absalon D Gutierrez and Nirav C Thosani are among the first physician-... (more)

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REBALANCE: Surgery vs. weight management

Surgery betters weight management as most effective treatment

10/01/19

Surgery remains the most effective and cost-effective long-term approach to reducing weight for adults adults with severe obesity, according to...

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17/01/19 - News

Owen Haskins

ERABS and renal failure

ERABS can be successfully deployed for end-stage renal failure

A study assessing the potential benefits and safety of the Enhanced Recovery After Bariatric Surgery (ERABS) protocol for end-stage renal disease (ESRD) has found that ERABS in this population has overall minimal adverse events and lack of any ERABS-related complications.

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16/01/19 - News

Owen Haskins

Variability in bariatric care pathways

Large variability in pre- and post-op care pathways in Scotland

Researchers from Scotland have reported a large nationwide variability in pre- and post-operative care pathways across Scotland, in a study that focused on pre-operative costs and the first 12 months following surgery. They note that the subsequent financial impact on the... (more)

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15/01/19 - News

Owen Haskins

Personality type and weight bias

Personality type could influence attitudes to body weight

Florida State University researchers suggest that the specific alchemy of an individual's personality - their distinct blend of conscientiousness, agreeableness, openness, neuroticism and extraversion - is directly related to their beliefs about others' bodies and the ways those... (more)

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14/01/19 - Research

VAT prioritisation

VAT prioritisation may cause pathogenic obesity

Type-2 (adult-onset) diabetes and other diseases related to the obesity epidemic depend on how the body stores excess energy, according to evolutionary biologist, Dr Mary Jane West-Eberhard, emeritus scientist at the Smithsonian Tropical Research Institute. West-Eberhard describes her theory about... (more)

11/01/19 - Research

Bile acids and bariatric surgery

Bile acids mediate metabolic benefits of bariatric surgery

A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signalling pathway in the positive metabolic effects of weight-loss surgery. The findings also suggest that the intestinal microbiome participates in post-surgery improvements and guide new treatment strategies... (more)

10/01/19 - Research

REBALANCE: Surgery vs. weight management

Surgery betters weight management as most effective treatment

Surgery remains the most effective and cost-effective long-term approach to reducing weight for adults adults with severe obesity, according to research from the University of Aberdeen, Aberdeen, UK Health Forum, London and the University of Oxford, Oxford, UK. However, the study also found that... (more)

09/01/19 - Research

Surgery and microbial strains

Bariatric surgery - new microbial strains in human faecal community

Using a unique bioinformatics technique, developed at the University of Alabama at Birmingham (UAB), researchers have detected the emergence of new strains of microbes in the human faecal microbiota after bariatric surgery. These new strains emerged after surgical disruption of the stomach and... (more)

09/01/19 - Research

Bariatric surgery and bleeding

EPT more accurate for bariatric surgery anticoagulant dosage

Endogenous thrombin potential (ETP), which measures the enzyme in blood plasma that causes blood to clot and bleeding risk, provides a more accurate assessment of the best dosage for various anticoagulants, according to researchers from Rutgers Ernest Mario School of Pharmacy. The results revealed... (more)

08/01/19 - Research

RYGB anaesthesia-related complications

Factors influencing RYGB anaesthesia-related complications

Post-operative nausea and vomiting (PONV) are the most common anaesthesia-related complication following Roux-en-Y gastric bypass, although this procedure has few anaesthetic complications, according to researchers University Hospital Zurich, Switzerland. The study authors found that factors... (more)